Table 1 Effect of allogenic blood transfusion in other studies involving head and neck cancer patients

From: The influence of allogenic blood transfusion in patients having free-flap primary surgery for oral and oropharyngeal squamous cell carcinoma

Author (year)

Disease

No. in study

Transfusion rate (%)

Outcome

Results

Taniguchi and Okura (2003)

Oral/oropharyngeal

105

32

5-year crude survival

P<0.01 (>3 units)

Moir et al (1999)

Larynx

165

36

Recurrence

P<0.04 (autologous vs heterologous)

Leon et al (1996)

Oral/oropharyngeal

269

32

Recurrence

No effect

 

Larynx/hypopharynx

    

Barra et al (1994)

Larynx/oral/oropharyngeal

207

73

5-year crude survival

P<0.05

Schuller et al (1994)

Larynx/oral/oropharyngeal

217

61

5-year crude survival

No effect

von Doersten et al (1992)

Larynx/paranasal/oral

104

49

Recurrence, infection

No effect

 

Oropharyngeal

    

Woolley et al (1992)

Larynx/hypopharynx

143

69

Recurrence

P<0.009

Alun-Jones et al (1991)

Larynx

69

55

5-year survival

P<0.05

Bock et al (1990)

Larynx/hypopharnyx

174

81

Recurrence, infection

No effect

    

5-year crude survival

 

Jones and Weissler (1990)

Larynx/oral/oropharyngeal

90

51

Recurrence

P<0.05

  1. All studies reporting a significant difference do so for worse outcome associated with allogenic blood transfusion.
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