Table 3 Association of factors with disease-specific survival for patients having free-flap surgery

From: The influence of allogenic blood transfusion in patients having free-flap primary surgery for oral and oropharyngeal squamous cell carcinoma

  

Disease specific

 

Patients

2 years

5 years

P -value *

Blood transfusion

 No

93

81

79

0.001

 <3 units

114

84

79

 

 3+ units

223

67

61

 

Gender

 Male

279

76

71

0.29

 Female

158

72

65

 

Age (years)

 <55

137

80

76

0.008

 55–64

125

73

66

 

 65–74

115

77

75

 

 75+

60

58

50

 

Tumour site

 Buccal

76

74

69

0.51

 Lower gum

47

79

74

 

 Tongue (ant. 2/3)

91

71

67

 

 Floor of mouth

132

78

73

 

 Other

91

72

64

 

ASA

 I

109

81

79

0.07

 II

210

74

66

 

 III/IV

80

71

64

 

 Unknown

38

68

62

 

Type of flap

 Soft

316

76

71

0.29

 Composite

119

71

66

 

Adjuvant radiotherapy

 No

220

81

77

0.002

 Yes

217

69

62

 

Mandibular resection

 Nil

237

77

73

0.11

 Rim

73

79

70

 

 Segment

127

68

63

 

ECS

 No ECS

320

83

77

<0.001

 ECS

117

52

46

 

Positive nodes

 No

237

86

81

<0.001

 Yes

200

61

55

 

Margins

 Clear >5 mm

192

89

84

<0.001

 Close <5 mm

149

71

64

 

 Involved

93

50

46

 

pT stage

 Tis, 1–2

224

82

77

<0.001

 3–4

211

66

61

 

pN

 0, no neck

230

87

82

<0.001

 1

78

73

68

 

 2–3

129

53

47

 

P stage

 1–2

127

90

86

<0.001

 3–4

308

68

62

 

Tumour differentiation

 Poor

55

58

52

<0.001

 Moderate

279

72

66

 

 Well

100

89

87

 

Pattern of invasion

 Favourable

105

91

88

<0.001

 Unfavourable

329

69

63

 

Perineural invasion

 No

307

80

74

<0.001

 Yes

130

60

56

 

Vascular invasion

 No

294

82

76

<0.001

 Yes

143

60

54

 
  1. ASA=American Society of Anesthesiologists; ECS=extracapsular spread. *Log-rank test. Table gives 2- and 5-year Kaplan–Meier survival rates.
Back to article page