Figure 1
From: MicroRNAs in cell proliferation, cell death, and tumorigenesis
The biogenesis and functions of cancer-associated human miRNAs. A simplified schematic of miRNA biogenesis is shown. MicroRNAs are initially transcribed by RNA polymerase II (Pol II) and sequentially processed by drosha and dicer (see text for details). MicroRNAs with tumour suppressing or oncogenic properties are shown with their experimentally validated targets.
