Table 3 Novel genes identified by DDD
From: Net1 and Myeov: computationally identified mediators of gastric cancer
Symbol | Name | UniGene ID | GA a | Non cancer a | Cancer a | Function |
|---|---|---|---|---|---|---|
AGR2 | Arginase, type II | Hs.226391 | 0.00242 | 0.00012 | 0.00017 | Urea cycle |
ANKRD9 | Ankyrin repeat domain 9 | Hs.432945 | 0.00098 | 0.00002 | 0.00004 | Function unknown |
ARHGEF16 | Rho guanine exchange factor 16 | Hs.87435 | 0.00032 | 0.00002 | 0.00002 | Function unknown |
BENE | BENE protein | Hs.185055 | 0.00059 | 0.00003 | 0.00004 | Function unknown |
C8G | Complement component 8, gamma polypeptide | Hs.1285 | 0.00016 | 0.00000 | 0.00000 | Complement activation |
CLDN18 | Claudin 18 | Hs.278966 | 0.00043 | 0.00003 | 0.00001 | Tight junction component |
CLDN2 | Claudin 2 | Hs.16098 | 0.00023 | 0.00002 | 0.00002 | Tight junction component |
EPS8L3 | EPS8-like 3 | Hs.5366 | 0.00021 | 0.00001 | 0.00002 | Receptor activity |
FBXL6 | F-box and leucine-rich repeat protein 6 | Hs.12271 | 0.00037 | 0.00002 | 0.00003 | Ubiquitin cycle |
GEFT | RAC/CDC42 exchange factor | Hs.61581 | 0.00027 | 0.00002 | 0.00003 | Cell proliferation |
KIAA1706 | KIAA1706 protein | Hs.412318 | 0.00034 | 0.00003 | 0.00001 | DNA binding |
KREMEN2 | Kringle containing transmembrane protein 2 | Hs.73452 | 0.00043 | 0.00000 | 0.00004 | Wnt signaling pathway |
MEIS4 | Likely ortholog of mouse myeloid ecotropic viral integration site-related gene 2 | Hs.356135 | 0.00043 | 0.00002 | 0.00004 | Transcription regulation |
MYEOV | Myeloma overexpressed gene | Hs.436000 | 0.00048 | 0.00000 | 0.00004 | Nucleic acid binding |
NET1 | Neuroepithelial cell transforming gene 1 | Hs.25155 | 0.00100 | 0.00008 | 0.00008 | Regulation of cell growth |
NOS3 | Nitric-oxide synthase activity | Hs.511603 | 0.00027 | 0.00002 | 0.00001 | Nitric-oxide synthase activity |
PARD6G | Par-6 partitioning defective 6 homolog gamma (Caenorhabditis elegans) | Hs.223584 | 0.00037 | 0.00001 | 0.00001 | Cytokinesis |
PTK2B | Protein tyrosine kinase 2 beta | Hs.438975 | 0.00094 | 0.00004 | 0.00005 | Signal transduction |
S100A14 | S100 calcium binding protein A14 | Hs.288998 | 0.00041 | 0.00001 | 0.00003 | Calcium ion binding |
SMCX | Smcx homolog, X chromosome (mouse) | Hs.103381 | 0.00066 | 0.00004 | 0.00004 | Transcription regulation |
THBS3 | Thrombospondin 3 | Hs.169875 | 0.00046 | 0.00004 | 0.00003 | Cell-matrix adhesion |
UNC93A | Unc-93 homolog A (C. elegans) | Hs.267749 | 0.00027 | 0.00000 | 0.00000 | Function unknown |
WBSCR21 | Williams beuren syndrome chromosome region 21 | Hs.182476 | 0.00043 | 0.00002 | 0.00004 | Aromatic compound metabolism |
