Table 4 Projections of 15-year survival probabilities based on data from Albertsen et al (1998) and Sweat et al (2002): central estimates and ranges of values obtained from low and high projections of life expectancy

From: A model of the natural history of screen-detected prostate cancer, and the effect of radical treatment on overall survival

  

Lead time (years)

Overdetection rate (%)

Albertsen data: survival benefit (%)

Sweat data: survival benefit (%)

Age group (years)

Gleason score

Central

Sensitivity range

Central

Sensitivity range

Central

Sensitivity range

Central

Sensitivity range

55–59

<7

14.1

5.2–22.1

37.1

6.9–82.4

0

0–5

0

0–6

 

=7

9.3

2.8–15.1

16.1

1.2–74.5

12

0–36

5

0–17

 

>7

5.0

1.1–9.6

7.3

0.2–78.6

26

1–48

12

0–23

60–64

<7

13.4

5.1–21.7

54.1

13.7–89.8

1

0–5

0

0–6

 

=7

9.2

2.7–15.3

27.8

4–78.2

9

0–32

4

0–18

 

>7

5.3

1.2–9.7

12.1

0.6–74.7

20

0–46

11

0–24

65–69

<7

11.8

4.4–20.1

66.9

19.4–94.4

0

0–7

0

0–4

 

=7

9.0

2.7–15.2

43.5

9.3–85.3

6

0–27

3

0–15

 

>7

6.0

1.4–10.1

25.8

3.4–77.4

12

0–40

6

0–22

70–74

<7

9.9

3.4–17.8

76.6

23.6–97.2

1

0–9

0

0–4

 

=7

8.0

2.3–14.3

57.5

15.2–91.1

3

0–22

2

0–15

 

>7

5.7

1.7–10.6

36.9

6.9–82.3

6

0–34

5

0–20