Table 4 Non-haematological (NTC CTC,Version 2.0) drug-related adverse events
N =63 pts | N =223 cycle | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Overall incidence | Grade 3 | Grade 4 | Overall incidence | Grade 3 | Grade 4 | |||||||
Nonhaematological | n | % | n | % | n | % | n | % | n | % | n | % |
Cardiac ischaemia | 1 | 1.6 | 0 | 0 | 1 | 1.6 | 1 | 0.4 | 0 | 0 | 1 | 0.4 |
Thrombosis/embolism | 1 | 1.6 | 0 | 0 | 1 | 1.6 | 2 | 0.9 | 0 | 0 | 2 | 0.9 |
Fatigue | 34 | 54.0 | 3 | 4.8 | 1 | 1.6 | 85 | 38.1 | 3 | 1.3 | 1 | 0.4 |
Anorexia | 10 | 15.9 | 2 | 3.2 | 0 | 0 | 12 | 5.4 | 2 | 0.9 | 0 | 0 |
Constipation | 40 | 63.5 | 6 | 9.5 | 0 | 0 | 93 | 41.7 | 6 | 2.7 | 0 | 0 |
Gastritis | 3 | 4.8 | 1 | 1.6 | 0 | 0 | 5 | 2.2 | 1 | 0.4 | 0 | 0 |
Stomatitis | 26 | 41.3 | 2 | 3.2 | 1 | 1.6 | 42 | 18.8 | 2 | 0.9 | 1 | 0.4 |
Abdominal pain | 18 | 28.6 | 2 | 3.2 | 0 | 0 | 27 | 12.1 | 3 | 1.3 | 0 | 0 |
Arthralgia | 3 | 4.8 | 3 | 4.8 | 0 | 0 | 4 | 1.8 | 3 | 1.3 | 0 | 0 |
Chest pain | 8 | 12.7 | 1 | 1.6 | 0 | 0 | 12 | 5.4 | 1 | 0.4 | 0 | 0 |
Myalgia | 18 | 28.6 | 8 | 12.7 | 2 | 3.2 | 45 | 20.2 | 9 | 4 | 2 | 0.9 |
Neuropathic pain | 9 | 14.3 | 1 | 1.6 | 0 | 0 | 18 | 8.1 | 1 | 0.4 | 0 | 0 |
2 | 2 | 3.2 | 1 | 1.6 | 0 | 0 | 3 | 1.3 | 1 | 0.4 | 0 | 0 |
ARDS | 1 | 1.6 | 0 | 0 | 1 | 1.6 | 1 | 0.4 | 0 | 0 | 1 | 0.4 |
