Table 3 Production of IFN-γ upon stimulation with autologous tumour extract.

From: Sentinel node lymphocytes: tumour reactive lymphocytes identified intraoperatively for the use in immunotherapy of colon cancer

 

SN

TIL

LN

PBL

Pat nr

BGa (pg ml−1)

Peakb (pg ml−1)

SI c

BGa (pg ml−1)

Peakb (pg ml−1)

SI c

BGa (pg ml−1)

Peakb (pg ml−1)

SI c

BGa (pg ml−1)

Peakb (pg ml−1)

SI c

 4

12

463

38,6

26

120

4,6

8

12

1,5

11

12

1,1

 5

30

107

3,7

13

13

1

10

13

1,3

7

7

1,0

 8

14

82

5,9

ND

ND

ND

62

688

11,0

16

93

5,8

13

97

1806

18,6

ND

ND

ND

ND

ND

ND

ND

ND

ND

14

6

14

2,3

ND

ND

ND

ND

ND

ND

ND

ND

ND

15

175

94

0,5

24

29

1,2

16

23

1,4

20

17

0,9

  1. SN, sentinel node; TIL, tumour infiltrating lymphocytes; LN, nonsentinel lymph nodes; PBL, peripheral blood leukocytes.
  2. ND=Not determined.
  3. aBG=Background, secretion of IFN-γ when cultured in complete medium alone, value from pooled triplicates.
  4. bThe highest amount of IFN-γ secreted upon stimulation with autologous tumour extract, value from pooled triplicates.
  5. cSI=stimulation index=peak/BG.
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