Figure 8 | British Journal of Cancer

Figure 8

From: Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01

Figure 8

Staurosporine (200 nM) is more potent than UCN-01 (500 nM) in mediating supra-additive enhancement of apoptosis in combination with low concentration of VA of 1.0 mM (#P=0.0022–0.0001 VA+STP vs VA+UCN-01). Data are expressed as mean±s.e.m. of three independent experiments.

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