Figure 4

Tissue platinum concentrations of the VX2 tongue tumour region from 46 rabbits after the administration of carboplatin. In comparison with i.v. infusion (n=26, median=7.98 μg g⁻¹), the i.a. infusion method showed a higher carboplatin concentration in the tongue tissue (n=20, median=80.45 μg g⁻¹) immediately after the administration of carboplatin. But 24 h after the administration of carboplatin, no difference in the tissue platinum concentration of i.a. and i.v.infusion was observed.