Figure 5

Spearman's correlation coefficients were used to evaluate the increase in the BVD correlated with the free platinum concentration of the tongue tissue. In the i.a. infusion group, the increase in the BVD was associated with a higher free platinum concentration in the tumour region. (Spearman ρ=0.797). However, no relationship was observed between the platinum concentration in the i.v. infusion group and in the normal region of the i.a. infusion group with the BVD.