Table 1 Patient characteristics

From: Phase II study of gefitinib in combination with docetaxel as first-line therapy in metastatic breast cancer

 

Patients ( N =41)

 

N

%

Age (years)

  

 Median

58

 Range

40–75

ECOG performance status

  

 0

39

95

 1

2

5

 2

0

0

Histology

  

 Ductal infiltrating carcinoma

37

90

 Lobular infiltrating carcinoma

4

10

ER expression (IHC)

  

 Positive

27

66

 Negative

14

34

HER-2 expression (IHC)

  

 3+

5

12

 Negative

22

54

 Unknown

14

34

Prior adjuvant therapy

  

 Yes

30

73

 No

11

27

 Prior adjuvant chemotherapy

30

73

 Prior adjuvant anthracyclines

22

54

 Prior adjuvant taxanes

6

15

 Prior adjuvant hormonotherapy (tamoxifen)

24

59

Dominant sites of disease

  

 Visceral

34

83

 Soft tissue (lymph nodes and bone sites)a

7

17

  1. aNo patient had only bone metastases.