Table 1 Standardized incidence ratios for a second primary cancer diagnosis by decade age at risk

	20–29		30–39 ^a		40–49		50–59		60–69		70+		50–59 ^b		60–69 ^b		70+ ^b			Percent
Age/Cancer	N	SIR	N	SIR	N	SIR	N	SIR	N	SIR	N	SIR	N	SIR	N	SIR	N	SIR	Total	%
All sites	78	17.3	1037	5.9	4547	2.37	2968	1.64					4720	2.67	10393	1.74	20506	1.33	44,249
Breast	65	478.5	857	21.8	3463	4.14	1507	2.19	387	1.45			3118	4.63	5268	2.83	8262	2.11	22,927	51.81
Other cancers	13	4.4	180	1.3			1461	1.3	526	0.9	71	0.8	1602	1.3	5125	1.3	12244	1.1	21,322	48.19
Bone	1	20.1	3	8.2			7	4.39							11	2.17			22	0.05
Brain	1	9.3																	1	0.00
Cervix uteri			39	0.5	140	0.55	57	0.68	8	0.35							160	0.72	404	0.91
Colon/Rectum									82	0.77	11	0.54	214	1.42	869	1.18	3145	1.07	4,321	9.77
Connective tissue			6	5.9											49	2.4	105	1.79	160	0.36
Corpus uteri							189	1.17	49	0.67			207	1.31	679	1.34	1273	1.61	2,397	5.42
Leukaemia	3	27.4			69	2.2	72	1.81					64	1.64	259	1.45			467	1.06
Lung			17	6.7	127	1.31	228	1.24					303	1.69	978	1.25	1854	1.12	3,507	7.93
Ovary	2	16	27	5	153	1.9	141	1.77					147	1.89	338	1.47	531	1.11	1,339	3.03
Pancreas			3	6.8									112	4.25			488	0.88	603	1.36
Skin			15				104	1.63	32	1.48			107	1.71	264	1.76	559	1.58	1,049	2.37
Stomach	1	145.4	1												11	0.14			13	0.03
Thyroid			17	1.9			46	1.64					61	2.23	77	1.53	113	1.38	314	0.71

All numbers represents an elevated risk that is statistically significant by 95% confidence intervals.
^aWomen diagnosed before age 30 are included if they did not have a primary tumour diagnosis before age 30. Subsequent tables accumulate cohorts similarly.
^bThe first diagnosis of breast cancer occurred at or after age 50.

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