Table 1 Patient characteristics

From: Increased expression of pAKT is associated with radiation resistance in cervical cancer

Characteristics

Radiation sensitive ( n =18)

Radiation resistant ( n =9)

P -value

Median age, years (range)

65 (38–80)

59 (36–73)

0.410

Stage

  

0.633

 IIB

11 (61%)

5(56%)

 

 IIIB

7 (39%)

3 (33%)

 

 IVA

 

1 (11%)

 

Cell type

  

1.00

 Squamous cell

18 (100%)

9 (100%)

 

Histologic grade

  

0.198

 I

6 (33%)

1 (11%)

 

 II

10 (56%)

6 (67%)

 

 III

2 (11%)

2 (22%)

 

Median tumour volume, cm3 (range)

19.1 (0.79–89.9)

31.4 (7.86–81.9)

0.777

Median OTT, days (range)

54.5 (41–77)

56 (50–74)

0.290

Median PFS, months (range)

70 (10–104)

9.0 (5–62)

<0.001

Recurrence

 Local

0

9

 

 Distant

1

1a

 

Current status

 NED

16

0

 

 AWD

0

3

 

 DOD

1

6

 

 DWOD

1

0

 
  1. OTT: overall treatment time; PFS: progression-free survival; NED: no evidence of disease; AWD: alive with disease; DOD: dead of disease; DWOD: dead without disease.
  2. aOne patient had local and paraaortic lymph node recurrence at the same time.