Table 1 Patient characteristics

From: FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients

Patients

 

n =198

Sex

  

 Male

 

105 (53%)

 Female

 

93 (47%)

Median age at diagnosis (years)

 

65 (range 23–93)

Date of diagnosis

 

1993–1999

pTNM UICC staging (n=198)

0: Tis, N0, M0

0 (0%)

 pT1: 0.75 mm

Ia: pT1, N0, M0

57 (29%)

 pT2: 0.76–1.5 mm

Ib: pT2, N0, M0

20 (10%)

 pT3a: 1.51–3.0 mm or level IV

IIa: pT3, N0, M0

34 (17%)

 pT3b: 3.01–4.0 mm or level IV

IIb: pT4a, N0, M0

10 (5%)

 pT4a: >4.0 mm or level V

IIIa: pT4a/pT4b, N1, M0

29 (15%)

 pT4b: Satellite met(s) within 2 cm from tumour

IIIb: any pT, N1/N2, M0

13 (6%)

 N1: Lymph node met(s) 3 cm

IV: any pT, any N, M1

35 (18%)

 N2a: Lymph node met(s) >3 cm

  

 N2b: In-transit met(s)

  

 N2c: Lymph node met(s) >3 cm and in-transit met(s)

  

 M: Distant met(s)

  

pTNM AJJC staging (n=139)

0: Tis, N0, M0

0 (0%)

 T1: 1.0 mm

Ia: T1a, N0, M0

39 (28%)

a: without ulceration; b: with ulceration or level IV or V

Ib: T1b, T2a, N0, M0

18 (13%)

 T2: 1.01–2.0 mm

IIa: T2b, T3a, N0, M0

12 (8%)

a: without ulceration; b: with ulceration

IIb: T3b, T4a, N0, M0

13 (9%)

 T3: 2.01–4.0 mm

IIc: T4b, N0, M0

5 (4%)

a: without ulceration; b: with ulceration

IIIa: T1-4a, N1a/N2a, M0

11 (7%)

 T4: >4.0 mm

IIIb: T1-4b, N1a/N2a, N1b/N2b

18 (13%)

a: without ulceration; b: with ulceration

T1-4a/b, N2c, M0

 

 N1: One lymph node

IIIc: T1-4b, N1b/N2b/N3, M0

5 (4%)

a: micrometastasis; b: macrometastasis

IV: any T, any N, M1

22 (16%)

 N2: 2–3 lymph nodes

  

a: micrometastasis; b: macrometastasis

  

c: in-transit met(s)/satellite(s) without metastatic lymph nodes

  

 N3: 4 lymph nodes, satellite(s) and metastatic lymph node(s)

  

 M1: Distant met(s)

  

Median follow-up time (months)

 

59 (range 2–141)

  1. Abbreviations: AJCC, American Joint Committee on Cancer; met(s), metastases; pTNM, tumour, lymph node and distant metastasis status; UICC, Union Internationale Contre le Cancer.