Table 1 Clinicopathological characteristics in patients undergoing potentially curative surgery with and without adjuvant 5-FU chemotherapy for colorectal cancer
No adjuvant 5-FU | Adjuvant 5-FU | P -value | |
---|---|---|---|
172 (%) | 50 (%) | ||
Age group (years) | |||
 <65 | 40 (23) | 26 (52) | |
 65–74 | 58 (34) | 18 (36) | |
 ⩾75 | 74 (43) | 6 (12) | <0.001 |
Sex | |||
 Male | 88 (51) | 33 (66) | |
 Female | 84 (49) | 17 (34) | 0.064 |
Site | |||
 Colon | 100 (58) | 28 (56) | |
 Rectum | 72 (42) | 22 (44) | 0.788 |
Dukes stage | |||
 A | 23 (13) | 0 (0) | |
 B | 96 (56) | 9 (18) | |
 C | 53 (31) | 41 (82) | <0.001 |
C-reactive protein | |||
 ⩽10 mg l−1 | 95 (55) | 32 (64) | |
 >10 mg l−1 | 77 (45) | 18 (36) | 0.270 |
Albumin | |||
 ⩾35 g l−1 | 132 (77) | 45 (90) | |
 <35 g l−1 | 20 (12) | 0 (0) | 0.01 |
Alive | 126 (74) | 35 (70) | |
Dead | |||
 Cancer specific | 23 (13) | 9 (18) | |
 Intercurrent | 23 (13) | 6 (12) | 0.709 |