Figure 5

Effect of doxorubicin on cell cycle profile of OS cell lines. SaOs-2, MG-63 and U2OS cells were cultured for 31 h in medium containing IC10 or IC90 doxorubicin as indicated. DNA histograms were made by PI staining and FACS flow cytometry. DNA histograms were analysed by ModFitLT cell cycle analysis software. Percent cells in G2/M phase of the cell cycle are indicated in the panels.