Table 1 IC50 values of Ad5-Δ24RGD, doxorubicin and cisplatin on OS cell lines

From: Different susceptibility of osteosarcoma cell lines and primary cells to treatment with oncolytic adenovirus and doxorubicin or cisplatin

OS cell line

Ad5-Δ24RGD (MOIa)

Doxorubicin (n M)

Cisplatin ( μ M)

SaOs-2

8.5±3.3b

37±16

2.3±0.8

MG-63

15.7±7.3

34±12

0.9±0.2

U2OS

1.1±1.2

280±190

5.6±3.0

  1. aMOI=multiplicity of infection; OS=osteosarcoma.
  2. bData are means with standard deviation from at least three independent experiments.
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