Table 1 Patients' characteristics

From: The role of haemoglobin level in predicting the response to first-line chemotherapy in advanced colorectal cancer patients

Total number of patients

631

Patients from centre #1

352

Patients from centre #2

53

Patients from centre #3

226

Male/female

385/246

Median age (range)

61.2 years (28.9–84.9)

Colon/rectum

464/167

PS 0/1/2/unknown

337/156/30/108

Stage at diagnosis

 A

2

 B

72

 C

169

 D

385

 Unknown

3

Previous adjuvant therapy

 Yes/no

172/459

Metastatic site at study entry

 1 mts site

450 (71.3%)

 >1 mts site

181 (28.7%)

 Liver

457/631 (72.4%)

 Lung

165/631 (26.1%)

 Abdomen

217/631 (34.4%)

 Bone

7/631 (1.1%)

Mean Hb level (±s.e.m.)

12.5 (±0.07) g dl−1

Male

12.8 (±1.8)

Female

12.0 (±1.5) (P<0.0001)

Colon

12.5 (±0.08)

Rectum

12.6 (±0.14) (P=NS)

PS 0

12.8 (±0.09)

PS 1

12.2 (±0.14)

PS 2

11.3 (±0.33) (P<0.0001)

1 mts site

12.5 (±0.08)

>1 mts site

12.4 (±0.14) (P=NS)

Liver mts

12.4 (±0.08)

No liver mts

12.7 (±0.13) (P=0.03)

Lung mts

12.4 (±0.08)

No lung mts

12.9 (±0.13) (P<0.01)

  1. mts=metastasis; NS=not significant.