Table 3 Correlation between VEGF-C/VEGFR-3 and clinicopathological factors

From: The balance of VEGF-C and VEGFR-3 mRNA is a predictor of lymph node metastasis in non-small cell lung cancer

Clinicopathological factors

No. of patients

VEGF-C/VEGFR-3

P -value

Age

 70>

40

2.24±2.89

0.58

 70

34

2.66±3.57

 

Gender

 Male

54

2.88±3.57

0.006

 Female

20

1.24±1.38

 

T

 1

28

1.79±2.22

0.27

 2

32

2.72±3.84

 

N

 (−)

48

1.77±2.44

0.03

 (+)

26

3.66±4.05

 

Stage

 I, II

51

2.19±2.84

0.34

 III, IV

23

2.97±3.91

 

Histological type

 Adenocarcinoma

39

1.70±2.02

0.04

 Squamous cell ca

32

3.40±3.40

 

Differentiation

 Adenocarcinoma

Well

16

1.08±1.12

0.08

Mod or Poor

23

2.12±2.39

 

 Squamous cell ca

Well

6

1.58±0.92

0.24

Mod or Poor

26

3.82±4.49

 
  1. VEGF-C: vascular endothelial growth factor-C;
  2. VEGFR-3: vascular endothelial growth factor receptor-3.