Table 1 Unadjusted and adjusted Cox proportional hazards regression analysis of 5-year survival of patients with cutaneous malignant melanoma
Variable | N | Unadjusted HR (95% CI) | Adjusted HR a (95% CI) |
|---|---|---|---|
Age | |||
Change per year | 3127 | 1.05 (1.05–1.06) | 1.04 (1.04–1.05) |
Sex | |||
Male | 1238 | 1.00 | 1.00 |
Female | 1899 | 0.57 (0.48–0.67) | 0.67 (0.56–0.80) |
Breslow b | |||
<1.5 mm | 2012 | 1.00 | 1.00 |
1.5–4.0 mm | 757 | 5.58 (4.49–6.92) | 3.62 (2.85–4.60) |
>4.0 mm | 358 | 12.23 (9.78–15.31) | 6.06 (4.64–7.93) |
Site b | |||
Head and neck | 553 | 1.00 | 1.00 |
Lower limb | 1104 | 0.48 (0.38–0.60) | 0.90 (0.70–1.17) |
Trunk | 832 | 0.65 (0.52–0.82) | 1.16 (0.91–1.50) |
Upper limb | 638 | 0.50 (0.39–0.65) | 0.91 (0.70–1.20) |
Histology b | |||
Acral lentiginous | 63 | 1.00 | 1.00 |
Lentigo maligna | 183 | 0.64 (0.36–1.14) | 0.82 (0.44–1.52) |
Nodular | 753 | 1.52 (0.94–2.44) | 1.28 (0.78–2.09) |
Superficial spreading | 2128 | 0.36 (0.22–0.57) | 1.02 (0.62–1.68) |
IMD quintile | |||
1 (affluent) | 1014 | 1.00 | 1.00 |
2 | 892 | 1.01 (0.80–1.27) | 1.06 (0.84–1.33) |
3 | 475 | 1.18 (0.91–1.53) | 1.08 (0.83–1.41) |
4 | 455 | 1.65 (1.30–2.11) | 1.53 (1.20–1.96) |
5 (deprived) | 274 | 1.63 (1.22–2.17) | 1.40 (1.05–1.88) |
Year | |||
Change per year | 3127 | 1.00 (0.97–1.03) | 1.00 (0.97–1.03) |
