Figure 3 | British Journal of Cancer

Figure 3

From: Has Cox-2 a prognostic role in non-small-cell lung cancer? A systematic review of the literature with meta-analysis of the survival results

Figure 3

Overall and subgroup analyses. Hazard ratio and 95% CI of survival in studies evaluating COX-2 status in NSCLC. HR>1 implies a survival disadvantage for the group with COX-2 expression. The square size is proportional to the number of patients included in the study and its extremities gives the 95% CI. The Figure 3 shows that there is a trend for a pejorative role of COX-2 as a prognostic survival in NSCLC and that the results become significant (CI not crossing 1) for the subgroups of stage 1 and of RT–PCR.

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