Table 2 Psychological outcomes, mean (s.d.)

From: Genetic nurse counsellors can be an acceptable and cost-effective alternative to clinical geneticists for breast cancer risk genetic counselling. Evidence from two parallel randomised controlled equivalence trials

 

Grampian

Wales

Outcomes

Nurse counsellor

Geneticist

Equivalence limit a

Difference b (95% CI)

Nurse counsellor

Geneticist

Equivalence limit

Difference b (95% CI)

STAI c

 Baseline

37.3 (13.6)

36.5 (12.8)

  

40.9 (15.1)

40.0 (14.5)

  

 Immediately after episode

36.4 (14.0)

34.4 (14.0)

±4.0

0.8 (−2.1 to 3.7)

38.1 (14.9)

38.9 (15.6)

±4.0

−1.5 (−4.5 to 1.5)

 Six months after episode

36.0 (13.5)

32.1 (11.7)

 

2.9 (−0.2 to 5.9)

38.9 (14.9)

38.1 (14.1)

 

0.6 (−2.9 to 4.1)

HADS

 Anxietyc

        

Baseline

6.7 (4.3)

6.4 (4.5)

  

8.1 (4.7)

7.4 (4.2)

  

Immediately after episode

6.3 (4.3)

5.5 (3.9)

±1.4

0.5 (−0.4 to 1.3)

7.0 (4.9)

7.1 (4.8)

±1.5

−0.4 (−1.3 to 0.5)

Six months after episode

6.2 (4.4)

5.5 (3.7)

 

0.1 (−0.7 to1.0)

7.4 (4.7)

6.4 (4.1)

 

0.5 (−0.6 to 1.5)

HADS

 Depressiond

        

Baseline

3.9 (3.7)

3.4 (3.4)

  

4.5 (3.7)

4.2 (3.8)

  

Immediately after episode

3.5 (3.6)

2.9 (2.8)

±1.2

0.3 (−0.4 to 1.0)

4.0 (3.8)

4.0 (3.8)

±1.2

−0.2 (−1.0 to 0.5)

Six months after episode

3.4 (3.6)

2.8 (2.9)

 

0.3 (−0.5 to 1.0)

4.5 (4.1)

3.9 (3.8)

 

0.6 (−0.4 to 1.5)

SF36

 Role emotionale

        

Baseline

80.5 (34.6)

82.6 (33.4)

  

74.4 (38.7)

71.0 (40.6)

  

Immediately after episode

81.6 (35.2)

82.5 (33.2)

±11.4

1.9 (−6.3 to 10.1)

74.8 (39.5)

71.5 (40.0)

±13.1

2.9 (−6.9 to 12.7)

Six months after episode

80.3 (35.9)

86.0 (30.7)

 

−2.5 (−11 to 5.9)

74.9 (38.7)

73.1 (42.2)

 

0.5 (−9.4 to 10.5)

SF36

 Mental healthe

        

Baseline

71.0 (18.2)

73.6 (17.7)

  

67.3 (18.8)

68.4 (19.3)

  

Immediately after episode

72.2 (18.6)

74.4 (17.7)

±6.0

0.6 (−2.9 to 4.1)

68.8 (20.5)

68.0 (21.3)

±6.3

1.3 (−2.7 to 5.2)

Six months after episode

72.3 (18.4)

77.4 (14.9)

 

−2.7 (−6.5 to 1.2)

67.1 (21.1)

67.4 (21.1)

 

0.3 (−4.2 to 4.8)

  1. aSet at ±4.0 for STAI, 1/3 of baseline s.d.s otherwise.
  2. bAdjusted for baseline.
  3. cHigher score indicates greater level of anxiety.
  4. dHigher score indicates greater level of depression.
  5. eHigher score indicates better health state.
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