Table 1 Relations between NGF expression and clinicopathological characteristics

From: Significance of nerve growth factor overexpression and its autocrine loop in oesophageal squamous cell carcinoma

 

NGF strong ( n =63)

NGF weak ( n =46)

P -value

Age (years)

 <63

28

(25.7%)

27

(24.8%)

0.142

 ⩾63

35

(32.1%)

19

(17.4%)

 

Gender

 Male

52

(47.7%)

39

(35.8%)

0.755

 Female

11

(10.1%)

7

(6.4%)

 

TNM

 T1/T2

24

(22.0%)

21

(19.3%)

0.429

 T3/T4

39

(35.8%)

25

(22.9%)

 

 N0

14

(12.8%)

22

(20.2%)

0.005

 N1

49

(45.0%)

24

(22.0%)

 

 M0

46

(42.2%)

42

(38.5%)

0.017

 M1a

17

(15.6%)

4

(3.7%)

 

TNM stage

 I/IIA–B

22

(20.2%)

26

(23.9%)

0.025

 III/IV

41

(37.6%)

20

(18.3%)

 

Histology

 Well/moderately

42

(38.5%)

39

(35.8%)

0.033

 Poorly

21

(19.3%)

7

(6.4%)

 

Location b

     

 U

8

(7.3%)

9

(8.3%)

0.553

 M

34

(31.2%)

21

(19.3%)

 

 L

21

(19.3%)

16

(14.7%)

 

TrkA expression

 Weak

14

(12.8%)

19

(17.4%)

0.032

 Strong

49

(45.0%)

27

(24.8%)

 

p75NTR expression

 Negative

39

(35.8%)

19

(17.4%)

0.033

 Positive

24

(22.0%)

27

(24.8%)

 
  1. aM1: All cases are with distant lymph nodes metastasis.
  2. bU=cervical and upper thoracic oesophagus; M=middle thoracic oesophagus; L=lower thoracic and abdominal oesophagus.
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