Figure 3

Principal component analysis reveals a time trend in protein expression during tumour progression (A). R2X(cum)=0.65 for the first two components. × and ▪ represent treated and untreated samples, respectively, and the different colours represent samples collected at different time points after treatment, as follows: blue=1 day; green=5 days; yellow=7 days; red=12 days. (B) and (C) display mean protein profiles within a specific spectral region, derived from untreated and treated samples, respectively. The samples are from the same time points as above and the same colour coding is applied.