Table 4 Top 10 three-way interactions from logistic regression

From: Interactions between genes involved in the antioxidant defence system and breast cancer risk

Loci

df

LRT

P -value

GPX4-02, TRX1-14 and TRXR2-04

26

29.64

0.00021

TRX1-14, TRX1-15 and TRXR2-04

25

28.68

0.00024

CAT-08, GSR-18 and SOD1-02

26

29.36

0.00025

TRX1-14, TRXR2-01 and TRXR2-04

26

29.10

0.00029

GSR-12, TRX1-14 and TRXR2-04

22

25.96

0.00032

SOD1-02,TRXR2-04 and TRXR2-08

26

28.52

0.00042

GPX1-01, GPX4-06 and TRXR2-03

26

28.51

0.00042

TRX1-14, TRX1-16 and TRXR2-10

23

26.29

0.00042

TRX1-14, TRXR2-04 and TRXR2-09

19

23.08

0.00047

GSR-16, SOD2-02 and TRXR2-05

26

28.04

0.00055

  1. The 10 three-way combinations with lowest P-value from the logistic regression (in descending order with the most significant first). The log-likelihood ratio statistic (LRT) is shown with degrees of freedom (df) and naïve P-value.
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