Table 8 Genotype frequencies and effect sizes for most significant two-way interaction with multifactor dimensionality reduction

From: Interactions between genes involved in the antioxidant defence system and breast cancer risk

 

TRXR2-05

 

0

1

2

Total

GSR-16

    

 0

748/701

596/505

108/125

1452/1331

 

1 (N/A)

0.90 (0.77–1.06)

1.24 (0.94–1.63)

1 (N/A)

 1

378/363

274/302

67/66

719/731

 

1.02 (0.86–1.22)

1.18 (0.97–1.43)

1.05 (0.74–1.50)

1.11 (0.98–1.26)

 2

55/32

24/39

8/5

87/76

 

0.62 (0.40–0.97)

1.73 (1.03–2.91)

0.67 (0.22–2.05)

0.95 (0.69–1.32)

Total

    
 

1181/1096

894/846

183/196

 
 

1 (N/A)

1.02 (0.90–1.16)

1.15 (0.93–1.43)

 
  1. Genotype frequencies and effect sizes for most significant two-way interaction with multifactor dimensionality reduction. Loci: GSR-16 and TRXT2-05. At each locus: 0=common homozygote, 1=heterozygote and 2=rare homozygote. In each cell: Controls/cases; odds ratio (95% CI).