Table 4 Percentage annual change in time from the onset of symptoms to diagnosis for 603 childhood CNS tumours in Denmark, 1980–1996

From: Increasing incidence of childhood tumours of the central nervous system in Denmark, 1980–1996

Tumour definition

n

% change per year

95% CI

P -value

All CNS tumours

603

−2.7

−5.2;−0.3

0.03

Tumour morphology

 Astrocytoma

241

−3.6

−7.3;0.1

0.06

Pilocytic astrocytoma

64

−0.3

–8.1;8.2

0.95

Other astrocytomasa

177

−4.6

−8.7;−0.2

0.04

 Primitive neuroectodermal tumours

108

−1.8

−6.2;2.9

0.45

 Ependymoma

53

−4.8

−10.5;1.3

0.13

 Other glioma

18

−18.6

−31.8;−2.9

0.04

 Others

183

1.1

−4.0;6.5

0.69

Not histologically verified

96

−1.7

−8.7;5.7

0.64

Tumour topography

 Cerebellum

176

−1.9

−5.8;2.1

0.34

 Cerebrum

170

−7.1

−11.7;−2.3

0.005

 Brain stem

78

−1.8

−8.0;4.8

0.59

 Other locations

179

−0.4

−5.0;4.4

0.86

  1. CI, confidence interval; CNS, central nervous system.
  2. Including astrocytomas, not otherwise specified.