Table 4 Percentage annual change in time from the onset of symptoms to diagnosis for 603 childhood CNS tumours in Denmark, 1980–1996
From: Increasing incidence of childhood tumours of the central nervous system in Denmark, 1980–1996
Tumour definition | n | % change per year | 95% CI | P -value |
|---|---|---|---|---|
All CNS tumours | 603 | −2.7 | −5.2;−0.3 | 0.03 |
Tumour morphology | ||||
Astrocytoma | 241 | −3.6 | −7.3;0.1 | 0.06 |
Pilocytic astrocytoma | 64 | −0.3 | –8.1;8.2 | 0.95 |
Other astrocytomasa | 177 | −4.6 | −8.7;−0.2 | 0.04 |
Primitive neuroectodermal tumours | 108 | −1.8 | −6.2;2.9 | 0.45 |
Ependymoma | 53 | −4.8 | −10.5;1.3 | 0.13 |
Other glioma | 18 | −18.6 | −31.8;−2.9 | 0.04 |
Others | 183 | 1.1 | −4.0;6.5 | 0.69 |
Not histologically verified | 96 | −1.7 | −8.7;5.7 | 0.64 |
Tumour topography | ||||
Cerebellum | 176 | −1.9 | −5.8;2.1 | 0.34 |
Cerebrum | 170 | −7.1 | −11.7;−2.3 | 0.005 |
Brain stem | 78 | −1.8 | −8.0;4.8 | 0.59 |
Other locations | 179 | −0.4 | −5.0;4.4 | 0.86 |