Table 2 Multivariable Cox proportional hazards analysis for progression-free and overall survival

From: Adjuvant chemotherapy vs radiotherapy in high-risk endometrial carcinoma: results of a randomised trial

 

Progression-free survival

Overall survival

 

HR (95%CI)

P

HR (95%CI)

P

Treatment arm

 Radiotherapya

1

0.64

1

0.85

 Chemotherapy

0.92 (0.65–1.30)

 

1.04 (0.72–1.50)

 

Age (years)

 <70a

1

0.009

1

0.001

70

1.71 (1.15–2.56)

 

1.99 (1.31–3.02)

 

Tumor grade

 1 or 2a

1

<0.0001

1

<0.0001

 3

2.74 (1.78–4.22)

 

3.09 (1.96–4.89)

 

Myometrial invasion

50%a

1

0.001

1

0.002

 >50%

2.20 (1.36–3.57)

 

2.22 (1.34–3.69)

 

Stage

 I or IIa

1

<0.0001

1

<0.0001

 III

2.70 (1.75–4.15)

 

3.17 (2.00–5.01)

 
  1. HR=hazard ratio, CI=confidence interval,
  2. aReference category