Table 2 Key prognostic variables in patients with elevations in c-reactive protein (CRP) prior to surgery

From: Preoperative elevation of serum C – reactive protein is predictive for prognosis in myeloma bone disease after surgery

Variable value

CRP <6 mg l−1 (n =26)

CRP 6 mg l−1 (n =45)

P -value

Age (yrs)

53.5±8.4

54.7±9.5

0.572

Gender (male:female ratio)

17 : 9

27 : 18

0.653

3 lytic lesions

18 (69.2%)

33 (73.3%)

0.711

M component type

 Bence Jones or IgD

6 (23.1%)

16 (35.6%)

0.273

β2-Microglobulin (mg l−1)

2.68±1.4

2.54±0.15

0.678

Serum albumin (g dl−1)

39.2±5.8

35.8±5.9

0.019*

LDH (U l−1)

168.4±48.1

192.4±70.8

0.123

Hemoglobin (g dl−1)

12.7±1.5

11.9±1.6

0.055*

Ca2+ (mmol l−1)

2.35±0.2

2.47±0.4

0.109

Serum creatinine (mg dl−1)

0.82±0.2

0.86±0.3

0.554

Best response to HDT+PBSCT

 Complete response (CR)

9 (34.6%)

12 (26.7%)

0.429

 Partial response (PR)

17 (65.4%)

33 (73.3%)

0.480

Prior local radiation

6 (23.1%)

19 (42.2%)

0.104

Surgery prior to initial treatment

15 (57.7%)

19 (42.2%)

0.209

Osteolyses in long bones

6 (23.1%)

19 (42.2%)

0.104

Postoperative complications

2 (7.7%)

5 (11.1%)

0.642

  1. Values shown are the mean±s.d.
  2. *Statistically significant at the 0.05 level.