Table 2 Key prognostic variables in patients with elevations in c-reactive protein (CRP) prior to surgery
Variable value | CRP <6 mg l−1 (n =26) | CRP ⩾6 mg l−1 (n =45) | P -value |
---|---|---|---|
Age (yrs) | 53.5±8.4 | 54.7±9.5 | 0.572 |
Gender (male:female ratio) | 17 : 9 | 27 : 18 | 0.653 |
⩾3 lytic lesions | 18 (69.2%) | 33 (73.3%) | 0.711 |
M component type | |||
Bence Jones or IgD | 6 (23.1%) | 16 (35.6%) | 0.273 |
β2-Microglobulin (mg l−1) | 2.68±1.4 | 2.54±0.15 | 0.678 |
Serum albumin (g dl−1) | 39.2±5.8 | 35.8±5.9 | 0.019* |
LDH (U l−1) | 168.4±48.1 | 192.4±70.8 | 0.123 |
Hemoglobin (g dl−1) | 12.7±1.5 | 11.9±1.6 | 0.055* |
Ca2+ (mmol l−1) | 2.35±0.2 | 2.47±0.4 | 0.109 |
Serum creatinine (mg dl−1) | 0.82±0.2 | 0.86±0.3 | 0.554 |
Best response to HDT+PBSCT | |||
Complete response (CR) | 9 (34.6%) | 12 (26.7%) | 0.429 |
Partial response (PR) | 17 (65.4%) | 33 (73.3%) | 0.480 |
Prior local radiation | 6 (23.1%) | 19 (42.2%) | 0.104 |
Surgery prior to initial treatment | 15 (57.7%) | 19 (42.2%) | 0.209 |
Osteolyses in long bones | 6 (23.1%) | 19 (42.2%) | 0.104 |
Postoperative complications | 2 (7.7%) | 5 (11.1%) | 0.642 |