Table 2 Genes upregulated and associated with group I (benign cluster) and group II (Malignant cluster) as determined by hierarchical clustering
Accession no. | Symbol | Genes upregulated in benign tumours |
---|---|---|
SOX10 | SRY (sex determining region Y)-box 10 | |
ALDH1A1 | Aldehyde dehydrogenase 1 family, member A1 | |
TPM2 | Tropomyosin 2 (beta) | |
COL6A1 | Collagen, type VI, alpha 1 | |
COL6A3 | Collagen, type VI, alpha 3 | |
MAPK1 | Mitogen-activated protein kinase 1 | |
SPARC | Secreted protein, acidic, rich in cysteine (osteonectin) | |
COL1A2 | Collagen, type I, alpha 2 | |
ERCC5 | Excision repair cross-complementing rodent repair deficiency, complementation group 5 | |
MATN2 | Matrilin 2 | |
GATM | Gycine amidinotransferase (L-arginine:glycine amidinotransferase) | |
D8S2298E | Reproduction 8 | |
MAOB | Monoamine oxidase B | |
SFRP1 | Secreted frizzled-related protein 1 | |
CCNT1 | Cyclin T1 | |
SPARCL1 | SPARC-like 1 (mast9, hevin, SC-1) | |
PBX3 | Pre-B-cell leukemia transcription factor 3 | |
LHFP | Lipoma HMGIC fusion partner | |
LRP6 | Low-density lipoprotein receptor-related protein 6 | |
IGFBP5 | Insulin-like growth factor binding protein 5 | |
CTGF | Connective tissue growth factor | |
CIS | Complement component 1, s | |
Accession no. | Â | Genes upregulated in malignant tumours |
OPCML | Opioid-binding protein/cell adhesion molecule-like | |
CDH6 | Cadherin 6, type 2, K-cadherin (fetal kidney) | |
NAP1 | Pronapsin A | |
MGC29643 | Hypothetical protein MGC299643 | |
STK4 | Serine/threonine kinase 4 | |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific) | |
CD24 | CD24 antigen | |
CDH1 | Cadherin 1, type 1, E-cadherin (epithelial) | |
TSPAN1 | Tetraspan 1 | |
GALNT3 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 | |
GFG18 | Fibroblast growth factor 18 | |
PAX8 | Paired box gene 8 | |
HOXB2 | Homeo box B2 | |
SLP1 | Secretory leukocyte protease inhibitor (antileukoprotease) | |
BF | B-factor, properdin | |
RAMP3 | Receptor (calcitonin) activity modifying protein 3 (RAMP3) |