Table 3 Identification of genes that distinguish among benign, borderline and malignant ovarian tumours by prediction analysis of microarrays

From: Gene expression profiling of human ovarian tumours

   

PAM Score

Accession no.

Symbol

Gene

Benign

Borderline

Malignant

H08561

IGFBP5

Insulin-like growth factor binding protein 5

0.2760

0

−0.0547

AA977242

CIRBP

Cold-inducible RNA-binding protein

0.2298

0

0

AA459941

PEG3

Paternally expressed 3

0.2251

0

0

AA001614

INSR

Insulin receptor

0.1515

0

0

AA424584

LTBP2

Latent transforming growth factor beta binding protein 2

0.1270

0

0

AA448277

FOXO1A

Forkhead box O1A (rhabdomyosarcoma)

0.1233

0

0

AA481438

SERPING1

Serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1

0.1197

0

0

AA700832

RBP1

Retinol binding protein 1, cellular

0.1105

0

0

AA481026

SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

0.1064

0

0

AA156802

LAMB2

Laminin, beta 2 (laminin S)

0.1022

0

0

AA056232

GSTM5

Glutathione S-transferase M5

0.0977

0

0

AA679454

STAR

Steroidogenic acute regulatory protein

0.0815

0

0

AA682423

MAOB

Monoamine oxidase B

0.0663

0

−0.0675

AA398366

SH3GL1

SH3-domain GRB2-like 1

0.0514

0

0

N78902

LEPR

Leptin receptor

0.0481

0

0

AA405767

PAX8

Paired box gene 8

0

0

0.0471

AA478553

DCT

Dopachrome tautomerase

0.0447

0

0

AA045735

Transcribed sequence with moderate similarity to protein sp:P39195

0.0345

0

0

AA460833

PGCP

Plasma glutamate carboxypeptidase

0.0147

0

0

AA490471

SPARCL1

SPARC-like 1 (mast9, hevin, SC-1)

0

0

−0.0093

W15267

LRP6

Low density lipoprotein receptor-related protein 6

0

0

−0.008

AA464856

ID4

Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein

0.0036

0

0

AI934925

SLC23A1

Solute carrier family 23 (nucleobase transporters), member 1

0

0

0.0013

R38201

OPCML

Opioid-binding protein/cell adhesion molecule-like

0

0

0.0012

H99676

COL6A1

Collagen, type VI, alpha 1

0.0005

0

0

  1. The score derived from this analysis using a significance threshold of 3.1 is shown.