Table 5 Correlation of AI and PI with stage, grade, response to immunotherapy and expression of Bcl-2 and Fas

From: Absence of Bcl-2 and Fas/CD95/APO-1 predicts the response to immunotherapy in metastatic renal cell carcinoma

 

AI (%, mean±s.d.)

P -value

PI (%, mean±s.d.)

P -value

T stage

 T1,2

0.675 (±0.693)

NS

5.002 (±3.189)

NS

 T3,4

0.511 (±0.558)

 

5.403 (±4.316)

 

Grade

 G1,2

0.603 (±0.625)

NS

4.629 (±3.179)

0.0287

 G3

0.260 (±0.174)

 

9.858 (±6.184)

 

Response

 CR+PR

0.380 (±0.281)

NS

6.635 (±6.127)

NS

 NC+PD

0.605 (±0.648)

 

4.945 (±3.288)

 

Bcl-2(+)

0.774 (±0.942)

NS

3.978 (±3.865)

0.0390

Bcl-2(−)

0.457 (±0.303)

 

5.911 (±3.943)

 

Fas(+)

0.626 (±0.667)

NS

5.442 (±2.796)

NS

Fas(−)

0.524 (±0.562)

 

5.187 (±4.593)

 
  1. AI=apoptosis index; CR=complete response; NS=not significant; PD=progressive disease; PI=proliferation index; PR=partial response; s.d.=standard deviation; NC=no changes.