Figure 3
Ultrastructure of adipocytes obtained from epididymal adipose tissue. Representative electron micrograph shows adipocytes from a control mouse containing a large lipid droplet and a thin rim of cytoplasm (A). Adipocytes from a tumour-bearing mouse show marked reductions in size with dilated interadipocyte space (B). Adipocytes from a tumour-bearing mouse showing thickened peripheral rim of cytoplasm that is mitochondria-rich and contains multiple small lipid droplets (C). Cell membrane aspect of adipocyte from a control mouse (D). Adipocyte from a tumour-bearing mouse exhibits irregular cell membrane projections (villous extroflexions) with cytoplasm containing enlarged and electron dense mitochondria (E). Higher magnification of the same cell shows mitochondria with increased cristae and dense inner matrix (F). L, lipid droplet; Cap, capillary; N, nucleus; m, mitochondrion; v, villous extroflexions.
