Table 2 Association between anaemia during pregnancy (haemoglobin concentration <11 g dl−1) and infant leukaemia

From: Maternal hemoglobin concentration during pregnancy and risk of infant leukaemia: a children's oncology group study

 

Odds ratio (95% CI) unadjusted

Adjusted a ODDS ratio (95% CI)

Overall leukaemia (n=178)

0.85 (0.53–1.37)

0.93 (0.57–1.53)

AML (n=63)

0.64 (0.32–1.30)

0.67 (0.32–1.37)

ALL (n=115)

0.98 (0.58–1.66)

1.14 (0.65–2.01)

MLL+ (n=92)

0.77 (0.42–1.40)

0.88 (0.47–1.63)

MLL− (n=62)

0.88 (0.45–1.73)

0.96 (0.48–1.91)

AML/MLL+ (n=21)

0.46 (0.13–1.64)

0.57 (0.16–2.07)

AML/MLL− (n=29)

0.72 (0.28–1.88)

0.70 (0.26–1.89)

ALL/MLL+ (n=71)

0.87 (0.46–1.65)

0.98 (0.50–1.91)

ALL/MLL− (n=33)

1.04 (0.45–2.39)

1.33 (0.55–3.24)

  1. aAssociation is adjusted for maternal race (white, black, Hispanic and other) and birth order (number of live births prior to index child). Maternal education (⩽HS, >HS ⩾college grad), household income (<$30 000, $30 000–$75 000, >$75 000), maternal age at time of index child's birth, child gender, smoking during pregnancy and birth weight were not significant confounders and are not included in the adjusted model.
Back to article page