Table 3 Exposure-age-concentration model: comparison of BEIR VI parameters (BEIR, 1999) with parameters estimated from the WISMUT cohort

From: Lung cancer risk among German male uranium miners: a cohort study, 1946–1998

 

BEIR VI

Wismut cohort

ERR/WLM (%)

0.83

0.25 (0.13–0.36)

Time since exposure (years)

  

 5–14

1.0

0.66 (0.44–0.89)

 15–24

0.78

1.0

 25+

0.51

0.50 (0.40–0.60)

Attained age (years)

  

 <55

1.0

1.0

 55–64

0.57

0.80 (0.64–1.0)

 65–74

0.29

0.66 (0.50–0.88)

 75+

0.09

0.49 (0.30–0.83)

Exposure rate or concentration (WL)

  

 <0.5

9.09

8.19 (4.36–15.4)

 0.5–1.0

4.45

4.27 (2.28–8.0)

 1.0–3.0

3.36

2.97 (1.93–4.57)

 3.0–5.0

2.91

2.52 (1.66–3.83)

 5.0–15.0

1.55

2.08 (1.39–3.13)

 15.0+

1.0

1.0

  1. BEIR=US National Academies, Nuclear and Radiation Studies Board (formerly: Board on Radiation Effects Research), Committee on the Biological Effects of Ionising Radiation; ERR=excess relative risk; WL=working level; WLM=working level month.