Table 1 Number of observed second primary cancers (Obs) following breast cancer, diagnosed between 1958 and 2000, standardised incidence ratios (SIRs), and 95% confidence interval (CI) among women

From: Family history of breast cancer and young age at diagnosis of breast cancer increase risk of second primary malignancies in women: a population-based cohort study

Second primary cancer site

Obs

SIR

95% CI

Upper aerodigestive tract

137

0.89

(0.75–1.04)

Salivary glands

43

1.67

(1.21–2.20)

Oesophagus

116

1.57

(1.24–1.78)

Stomach

686

1.40

(1.30–1.51)

Small intestine

76

1.29

(1.02–1.60)

Colorectum

1923

1.15

(1.10–1.20)

Liver

451

0.92

(0.84–1.01)

Pancreas

471

1.12

(1.02–1.22)

Lung

717

1.37

(1.27–1.47)

Cervix

217

0.92

(0.80–1.05)

Endometrium

1006

1.54

(1.44–1.63)

Ovary

712

1.28

(1.19–1.38)

Kidney

443

1.31

(1.19–1.44)

Urinary organs

383

1.10

(0.99–1.21)

Melanoma

360

1.27

(1.14–1.40)

Nervous system

367

1.16

(1.05–1.28)

Thyroid

164

1.55

(1.32–1.80)

Endocrine glands

270

1.08

(1.96–1.22)

Bone

21

1.68

(1.04–2.48)

Connective tissue

129

1.78

(1.49–2.10)

Non-Hodgkin's lymphoma

390

1.13

(1.02–1.25)

Hodgkin's disease

38

1.05

(0.74–1.41)

Multiple myeloma, plasmocytoma

182

1.04

(0.89–1.20)

Leukaemia

343

1.37

(1.23–1.52)

All the above sites

9758

1.22

(1.19–1.24)

  1. Bold denotes statistical significance.