Table 2 Number of observed second primary cancers (Obs) following breast cancer, diagnosed between 1958 and 2000, standardised incidence ratios (SIRs), and 95% confidence interval (CI) for second primary malignancy according to age at breast cancer diagnosis

20

2.54

(1.55–3.78)

96

1.38

(1.12–1.67)

1.84*

97

2.18

(1.77–2.63)

589

1.32

(1.22–1.43)

1.65*

278

1.38

(1.23–1.58)

1645

1.12

(1.06–1.17)

1.24*

74

1.60

(1.26–1.99)

397

1.06

(0.96–1.16)

1.51*

235

2.35

(2.06–2.66)

482

1.14

(1.04–1.24)

2.07*

183

1.29

(1.11–1.49)

823

1.61

(1.50–1.72)

0.80*

247

1.97

(1.73–2.22)

465

1.08

(0.98–1.18)

1.82*

74

1.50

(1.18–1.86)

369

1.28

(1.15–1.41)

1.17

91

1.32

(1.06–1.61)

269

1.25

(1.10–1.40)

1.06

89

1.25

(1.00–1.52)

278

1.14

(1.01–1.27)

1.10

51

2.21

(1.65–2.86)

113

1.36

(1.12–1.63)

1.62*

75

1.36

(1.07–1.68)

195

1.01

(0.87–1.15)

1.35*

40

3.27

(2.33–4.36)

89

1.48

(1.19–1.80)

2.21*

19

8.02

(4.82–12.03)

42

3.46

(2.49–4.58)

2.32*

77

1.51

(1.19–1.87)

313

1.06

(0.95–1.19)

1.42*

61

1.81

(1.38–2.29)

282

1.30

(1.15–1.46)

1.39*

2

1.20

(0.14–3.45)

20

2.19

(1.34–3.26)

0.55

14

1.15

(0.63–1.84)

87

0.96

(0.77–1.17)

1.21

22

1.97

(1.23–2.88)

91

1.46

(1.17–1.77)

1.35

13

2.89

(1.53–4.67)

33

1.56

(1.08–2.14)

1.85

1692

1.64

(1.56–1.72)

6405

1.20

(1.17–1.23)

1.36*