Table 1 Associations between the FGFR4 genotype and demographic characteristics, smoking status, pathological parameters, and TP53 mutation status in 125 patients with bladder cancer
Gly/Gly, n (%) | Gly/Arg, n (%) | Arg/Arg, n (%) | P -value | |
|---|---|---|---|---|
All patients | 59 (47.2) | 53 (42.4) | 13 (10.4) | |
Age at diagnosis (years±s.d.) | 67.0±9.6 | 64.7±10.9 | 69.7±9.5 | 0.220 |
Age(years) | ||||
>66 | 35 (59.3) | 29 (54.7) | 8 (61.5) | 0.868 |
≤66 | 24 (40.7) | 24 (45.3) | 5 (38.5) | |
Gender | ||||
Male | 45 (76.3) | 42 (79.3) | 10 (76.9) | 0.952 |
Female | 14 (23.7) | 11 (20.7) | 3 (23.1) | |
Smoking status | ||||
Current | 7 (13.2) | 7 (14.6) | 1 (7.7) | 0.885 |
Former | 36 (67.9) | 32 (66.7) | 8 (61.5) | |
Never | 10 (18.9) | 9 (18.7) | 4 (30.8) | |
Stage | ||||
I | 4 (6.8) | 3 (5.7) | 1 (7.7) | 0.993 |
II | 5 (8.5) | 5 (9.4) | 1 (7.7) | |
III | 45 (76.2) | 41 (77.4) | 11 (84.6) | |
IV | 5 (8.5) | 4 (7.5) | 0 (0) | |
Grade | ||||
G1 | 3 (5.2) | 3 (5.8) | 0 (0) | 0.924 |
G2 | 9 (15.5) | 11 (21.1) | 2 (15.4) | |
G3-4 | 46 (79.3) | 38 (73.1) | 11 (54.6) | |
Lymph node involvement | ||||
Present | 22 (37.3) | 22 (41.5) | 7 (53.8) | 0.545 |
Absent | 37 (62.7) | 31 (58.5) | 6 (46.2) | |
Vascular invasion | ||||
Yes | 31 (52.5) | 27 (50.9) | 8 (61.5) | 0.842 |
No | 28 (47.5) | 26 (49.1) | 5 (38.5) | |
TP53 mutation | ||||
Yes | 26 (44.1) | 22 (41.5) | 10 (76.9) | 0.076 |
No | 33 (55.9) | 31 (58.5) | 3 (23.1) | |
