Table 2 Hazard ratios of death from bladder cancer for the FGFR4 Gly388 polymorphism and TP53 mutation status in 125 cancer patients

From: Joint association of polymorphism of the FGFR4 gene and mutation TP53 gene with bladder cancer prognosis

 

No.

Death

Death (%)

Hazard ratio a

95% CI

P -value

FGFR4 genotype

 Gly/Gly

59

38

64

1.42

(0.83–2.40)

0.198

 Arg/Arg+Arg/Gly

66

34

52

ref.

  

TP53 status

 Abnormal

62

38

61

1.53

(0.88–2.65)

0.133

 Normal

63

34

54

ref.

  

FGFR4/TP53

 Gly/Gly/abnormal

28

21

75

2.25

(1.04–4.88)

0.039

 Gly/Gly/normal

31

17

55

1.28

(0.58–2.83)

0.538

 Arg/Arg+Arg/Gly/ abnormal

34

17

50

1.38

(0.63–3.04)

0.423

 Arg/Arg+Arg/Gly/ normal

32

17

53

ref.

  

 Gly/Gly+abnormal

28

21

75

1.85

(1.01–3.39)

0.046

 Other

97

51

53

ref.

  
  1. aHazard ratios were adjusted for age, gender, lymph node involvement, tumour stage and grade.