Figure 4 | British Journal of Cancer

Figure 4

From: Histamine, a vasoactive agent with vascular disrupting potential, improves tumour response by enhancing local drug delivery

Figure 4

Albumin extravasation and tumor endothelial cell matrix alterations. Upper panel shows MSB staining for connective tissue and fibrin with a clear disarrangement of collagen fibres seen in tumours submitted to Hi-based ILP. Lower panel depicts most representative slides of Immunohistochemistry staining with antialbumin where albumin appears in brown, surrounding the vessels in the Hi-treated tumor tissues. More striking effects were clearly observed after Hi+DXR ILP. Original magnification × 16.

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