Table 3 Kaplan–Meier and Cox regression analysis of survival and time to progression data

From: Effect of treatment with epoetin beta on short-term tumour progression and survival in anaemic patients with cancer: a meta-analysis

 

Control ( n =613)

Epoetin beta ( n =800)

 

Patient group

Total events

Mean patient-years of follow-up

Events per patient-year

Total events

Mean patient-years of follow-up

Events per patient-year

Hazard ratio (95% CI)

Overall survival

       

Total

58

0.30

0.32

80

0.32

0.31

0.97 (0.69–1.36)

Tumour type

       

 Solid

17

0.25

0.24

22

0.32

0.21

0.94 (0.50–1.78)

 Haematological

41

0.34

0.37

58

0.32

0.39

1.04 (0.69–1.55)

Time to progression

       

 Total

133

0.27

0.81

145

0.29

0.62

0.78 (0.62–0.99)

Tumour type

       

 Solid

50

0.23

0.78

50

0.30

0.50

0.71 (0.48–1.06)

 Haematological

82

0.31

0.81

93

0.29

0.69

0.84 (0.62–1.13)

  1. ‘Events’ refers to number of deaths for ‘overall survival’, and to number of malignant disease progressions for ‘time to progression’.