Figure 1
From: The expression of FHIT, PCNA and EGFR in benign and malignant breast lesions
Staining patterns in four breast lesions. Upper row (H&E). Cancer (A and D), DCIS (B) and hyperplasia (C). Lower row (ISH). Cancer (A), DCIS (B) and hyperplasia (C) dually stained with antibodies to FHIT (brown) and PCNA (red). (D) Cancer stained with antibody to EGFR (brown) and haematoxylin (blue). Arrows indicate different staining patterns: PCNA (i) trabeculated, (ii) intense, (iii) cloudy, (iv) cloudy and EGFR (v) membrane-associated.
