Table 5 Univariate analysis for patients with relapsed disease
From: A comparison of patients with relapsed and chemo-refractory gestational trophoblastic neoplasia
GTN-related deaths | ||||
|---|---|---|---|---|
Yes | No | P -value | ||
Median age at relapse (years) | 32 | 29 | 0.26 | |
Median hCG at presentation | 15 000 | 28 000 | 0.14 | |
Median interval between causal pregnancy and first chemotherapy | 1.1 years | 0.5 years | 0.57 | |
Maximum hCG at relapse (medium) | 350 | 121 | 0.41 | |
HCG doubling time at relapse (days) | 15 | 7 | 0.01* | |
Lung metastasis at presentation | No | 2 | 42 | 0.11 |
Yes | 3 | 13 | ||
Nonpulmonary metastasis at presentation | No | 3 | 52 | 0.05* |
Yes | 2 | 3 | ||
Treatment at initial presentation | High risk | 5 | 20 | 0.01* |
Low risk | 0 | 35 | ||
Interval between chemotherapy and relapse | 0–3 months | 4 | 30 | 0.19 |
>3 months | 1 | 25 | ||
Metastasis identified at relapse | No | 1 | 39 | 0.03* |
Yes | 4 | 16 | ||
Uterine mass identified at relapse | No | 3 | 24 | 0.65 |
Yes | 2 | 31 | ||
Nonpulmonary metastasis at relapse | No | 4 | 52 | 0.30 |
Yes | 1 | 3 | ||
Causal pregnancy | Mole | 0 | 29 | 0.02* |
Term | 5 | 26 | ||
