Table 2 Clinical status of NPC cases detected

From: Sustained elevation of Epstein–Barr virus antibody levels preceding clinical onset of nasopharyngeal carcinoma

  

AJCC/UICC stage

Detection

Number of NPC cases

I

II

III

IV

% I and II

Routine screening:

74

44

6

16

8

67.6

After onset of symptoms

97

7

12

38

40

19.6

New cases referred to our clinic

1629

173

164

578

714

20.7

  1. AJCC/UICC=American Joint Committee of Cancer/International Union Against Cancer; NPC=nasopharyngeal carcinoma.
  2. One hundred and seventy-one NPC cases were detected from study subjects either by clinical examination during routine screening, or when patients presented with symptoms of NPC (see Table 1 for details). Newly diagnosed cases, usually with presence of symptoms and referred to our out-patients clinics during the same time, served as concurrent control cases. Percentage of stages I and II cases detected by routine screening is significantly higher than that detected after onset of symptoms (χ2=154.88, P=0.000), and that of the latter is similar as new cases referred to our clinics (χ2=1.984, P=0.576).