Table 3 General mental health and cancer specific worry

From: Predictive genetic testing for BRCA1/2 in a UK clinical cohort: three-year follow-up

 

Baseline

3-year follow-up

 
 

Carriers

Non-carriers

Carriers

Non-carriers

P *

GHQ females

     

 Mean (s.d)

2.7 (4.6)

2.6 (3.8)

4.5 (6.3)a

3.7 (5.3)

0.3

 Median (range)

0 (0–20)

1 (0–15)

1 (0–27)

1 (0–24)

 

GHQ males

     

 Mean (s.d)

0.8 (2.6)

1.9 (3.5)

1.6 (3.6)

2.5 (5.1)

0.8

 Median (range)

0 (0–11)

0 (0–12)

0 (0–12)

0 (0–17)

 

GHQ case (⩾10)

     

 n female

6 (12%)

8 (8%)

9 (18%)

16 (17%)

1.0

 n male

1 (6%)

2 (10%)

2 (11%)

2 (10%)

 

CWS-R females

     

 Mean (s.d)

11.7 (3.1)

11.5 (3.4)

10.4(3.6)a

9.3 (2.1)

0.2

 Median (range)

11 (6–21)

11 (6–22)

10 (6–21)

9 (6–15)

 

CWS-R males

     

 Mean (s.d)

Not measured

8.2 (2.0)

8.1 (2.0)

 

 Median (range)

  

8 (6–13)

8 (6–11)

 
  1. GHQ with binary scoring and ⩾10 cutoff to indicate cases.
  2. *Comparison of the change from baseline of carriers vs non-carriers.
  3. aSignificant change from baseline P=0.03.
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