Table 3 Relative risk associated with the use of progestagens according to duration and recency of use, compared with never use (n=73 664). E3N cohort study (1990–2002)
From: Oral progestagens before menopause and breast cancer risk
Duration of use (years) | ||||||
---|---|---|---|---|---|---|
<4.5 | ⩾4.5 | |||||
Recency of use | [PY; cases] | RR a | 95% CI | [PY; cases] | RR a | 95% CI |
Current use | [58 751;193] | 1.09 | 0.92–1.29 | [9 946;42] | 1.44 | 1.03–2.00 |
Past use | [132 341;525] | 0.97 | 0.87–1.07 | [23 193;120] | 1.06 | 0.88–1.27 |
Trend (per year since last use) | 0.99 | 0.98–1.01 | 0.97 | 0.95–1.01 |