Table 2 Alcohol consumption in relation to colorectal cancer, Singapore Chinese Health Study, 1993–2004

From: Cigarettes and alcohol in relation to colorectal cancer: the Singapore Chinese Health Study

  

Colorectal cancer

Colon cancer

Rectal cancer

Alcohol drinking

Person-years

Cases

HR (95% CI) a

Cases

HR (95% CI) a

Cases

HR (95% CI) a

Total subjects

Number of drinks/week

 Nondrinker

443968

658

1.00

416

1.00

242

1.00

 <7

77374

117

0.96 (0.72–1.25)

60

0.96 (0.72–1.25)

57

1.22 (1.07–2.35)

 7+

25177

70

1.84 (1.31–2.58)

40

1.84 (1.31–2.35)

30

1.59 (1.07–2.35)

 P for trend

  

0.0004

 

0.01

 

0.01

Never smokers

Number of drinks/week

 Nondrinker

333894

428

1.00

 

1.00

128

1.00

 <7

44022

52

1.05 (0.78–1.44)

300

0.88 (0.60–1.30)

23

1.40 (0.89–2.22)

 7+

7844

15

1.46 (0.87–2.46)

29

1.33 (0.68–2.59)

6

1.75 (0.76–4.02)

 P for trend

  

0.23

9

0.91

 

0.06

Ever smokers

       

Number of drinks/week

       

 Nondrinker

110073

230

1.00

116

1.00

114

1.00

 <7

33352

65

1.06 (0.71–1.58)

31

1.06 (0.71–1.58)

34

1.11 (0.75–1.63)

 7+

17333

55

1.80 (1.33–2.42)

31

2.12 (1.42–3.18)

24

1.49 (0.95–2.33)

 P for trend

  

0.0007

 

0.002

 

0.099

  1. aAll hazard ratios (HRs) were calculated using the Cox regression models that also included the following covariates: age, gender, dialect group, year of recruitment, level of education, body mass index, history of diabetes, family history of colorectal cancer, cigarette smoking level (for total and ever smokers only), and physical exercise (see details in the Method section).
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