Figure 4
Fluence-dependent mitochondria membrane photodamage. (A, B) Fluence-dependent cyt c release and (C, D) mitochondrial membrane depolarisation in Foscan®-photosensitised MCF-7 cells. MCF-7 cells were incubated with 1.5 × 10−6 M Foscan® for (A, C) 3 h or (B, D) 24 h and subjected to equitoxic light doses. Photosensitised MCF-7 cells were analysed immediately (□) and 24 h after irradiation (▪). Results are the mean±s.e.m. of at least three independent experiments. *, significantly different from control values.
