Figure 4

Inhibition of CEM/A7R cells by combined use of anti-Cripto Mab C13 with different concentrations of EPI at 0.11 to 1 μg ml⁻¹ (A), DAU at 0.04–0.33 μg ml⁻¹ (B) or C4 at various concentrations with Arac at 0.0015, 0.003 and 0.005 μg ml⁻¹ (C) after 48 h incubation as measured by percentage of control in [³H]thymidine incorporation. Points are means of triplicate experiments. Error bars represent s.d. in triplicate experiments. The interactions of various concentrations of C13 with EPI, DAU or C4 with AraC were subjected to two-way ANOVA. The P-values were marked as ^*P<0.05, ^** P< 0.01, ^*** P< 0.001.