Table 1 Patients' demographic characteristics of patients undergoing hepatic resection for colorectal liver metastasis with and without neo-adjuvant chemotherapy; control group vs chemotherapy group
From: Safe liver resection following chemotherapy for colorectal metastases is a matter of timing
Control ( n =245) | Chemotherapy ( n =252) | P -value | |
|---|---|---|---|
Age at liver surgery; mean (s.d.) years | 63 (10.8) | 62 (9.8) | 0.098a |
Male gender | 163 (67%) | 168 (67%) | 1.0b |
Performance status; n (%) | 0.028b | ||
Normal/minimal reduction | 166 (67.8%) | 149 (59.1%) | |
Clear reduction | 79 (32.2%) | 103 (40.9%) | |
Duke's Stage of primary tumour; n (%) | <0.001b | ||
Dukes' A or B | 145 (59.2%) | 79 (31.3%) | |
Dukes' C | 99 (40.4%) | 167 (66.3%) | |
Timing of liver metastases; n (%) | <0.001b | ||
Synchronous | 95 (38.8%) | 151 (59.9%) | |
Metachronous | 150 (61.2%) | 101 (40.1%) | |
Number of liver metastases; n (%) | 0.26b | ||
1–3 | 211 (86.1%) | 207 (82.1%) | |
>3 | 33 (13.5%) | 43 (17.1%) | |
Size of liver metastases; n (%) | 0.64b | ||
<5 cm | 164 (66.9%) | 173 (68.2%) | |
>5 cm | 81 (33.1%) | 78 (31.0%) |
